The college was established on June 16, 1944. Founded by Rev. Fr. John Berchmans CMI and Rev. Fr. Francis Sales CMI. Rev. Fr. Peter Thomas Pynumkal CMI was appointed as its first Principal. College started with 276 students in the three intermediate and three degree programmes affiliated to Madras University. The courses offered at the degree level were Commerce, Mathematics and Economics.
Affiliation was granted to B Sc programme in Chemistry. The ebullient Prof. M.V. Varghese and Prof. K.A. Gopalakrishnan, are said to have established the department as a strong academic unit.
Affiliation was granted for B. Sc Zoology programme, which ably guided by the great institution builder, Padmabhushan Rev. Fr. Gabriel, Rev. Dr. Theobald & Prof. T.C. Mathew. Rev. Fr. Gabriel is credited to have been the brain behind the well laid out Zoology museum with its very unique collections. In 1956, he left the department to establish Christ College, at Irinjalakkuda, the second venture of the CMIs in higher education.
The college secures MG University Overall Championship in sports.